They’ll never admit it, but viewers love sex. In fact, they love any sort of titillation, with the exception of incest. So focus on that.
Ah, so what not to do. From Wikipedia:
Several of the major characters of the show are at some stage involved in a plot with incestuous themes.[13] Frequently, this theme is linked with questions about murky family lineage. For example, George Michael and Maeby spend most of the series struggling to contain a mutual attraction, despite the fact that they believe themselves to be cousins. There is also Maeby’s interest in Steve Holt, who is also revealed to be her cousin. In the second season, the episode “Afternoon Delight” plays on this theme when Michael and Maeby (and later George Michael and Lindsay) sing the Starland Vocal Band song “Afternoon Delight”, being unaware of its sexual nature. Oscar also (very blatantly) hints that he is Buster’s real father, through his relationship with Lucille. When Buster first learns of the truth, he exclaims, “My father is my uncle!” This theme is also explored in the episode “Family Ties,” through the character of Nellie Bluth, who Michael thinks for a time might be his older sister, but who herself presumes Michael is interested in her for sex. The fact that Nellie Bluth is played by Jason Bateman’s real life sister Justine Bateman (who also starred in the 1980s sitcom Family Ties) lends the plot line an additional layer of comic complication. In addition, Rita, Michael’s mentally challenged girlfriend, has her limited mental capabilities attributed to her parents being cousins. In yet another example of this theme, upon discovering her adoption, Lindsay attempts to seduce her brother, Michael. Gob, out of brotherly competition, later attempts to seduce her. Another running joke throughout the series was Buster’s Oedipal obsession with his mother. This strange relationship is highlighted in the episode “Motherboy XXX,” where Buster says, “Whenever she’d change clothes, she’d make me wait on the balcony until zip-up—and yet anything goes at bath-time.” Buster’s mixed feelings about his mother are also shown through his relationship with his girlfriend and mother’s best friend Lucille Austero, played by Liza Minelli, known as “Lucille 2.”
Amazing.